Q&A for How to Catch Heatran in Pokémon Black 2 and White 2

No, if you run away from Heatran, you cannot re-encounter it in the same playthrough. To have another chance, you must reload a previous save file from before you initiated the battle.

To avoid running out of Poké Balls, you can either purchase a larger supply or significantly weaken the Pokémon before attempting to capture it to increase your success rate.

To get a shiny Heatran, save your game directly before battling it. If it is not shiny, restart your game and re-engage it in battle. Repeat this process until a shiny Heatran appears, which you can identify by its unique color palette and sparkling animation.

If you accidentally defeat Heatran, you should turn off your DS and restart from your most recent save point.